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It is known that microgravity increases intracranial pressure (ICP), causes space flight-associated neuro-ocular syndrome (SANS), damages cerebral blood flow, causing orthostatic intolerance, headache, and impaired neurocognitive performance in astronauts. Rheoencephalography (REG) is a non-invasive method to study cerebral blood flow and its autoregulation. A recent clinical study demonstrated that REG pulse wave morphology shows identical alteration as intracranial pressure by reflecting decreased intracranial compliance caused by ICP elevation, increasing the 2nd pulse peak.

Invasive measurements of intracranial pressure on the International Space Station (ISS) and during space flights are not feasible. The use of a miniaturized REG device thus therefore become a cheap and practical, non-invasive measurement possibility in space environments. This website hosts the support software required to operate our miniaturized REG device.

Click on the Download link in the header to download the software or on the User Guide link to read the user manual. You will also need the device itself and a USB-C cable to connect the device to the computer running the support software to make measurements.